My dog was diagnosed by my vet as having protein losing nephropathy and was put on Enalapril. She was tested 2x for Cushings Disease and came up negative. Her protein level has been tested every few months, she was switched to Science Diet prescription KD food and I reduced her food amount. Her protein levels still are increasing (not by much) so the vet keeps increasing dosage of Enalapril. Yet she is still panting, not losing weight at all. At my wits end!

My dog was diagnosed with protein losing nephropathy a year and half ago. He has been doing ok until recently. Within the last two months he has lost weight in addition to losing his appetite. He has begun appearing a bit lethargic as well. I took him to my vet a week ago and his kidney numbers and urinalysis were good. He isn't losing a lot of protein and his kidneys aren't great but appear to be stable. They also checked for parasitic infections and those were negative as well. The vet's diagnosis was my dog was just a picky eater and to try different foods to get his appetite and weight back up. I have tried many foods and my dog will just eat enough to sustain himself. He no longer eats filling meals. I have noticed he appears to have difficulty chewing, and my vet did say his teeth were decaying due to his disease. I'm not sure this could be contributing to his eating habits. Also he has started to appear to have difficulty producing solid stools. Any advice would be greatly appreciated, as I love my dog and would like to keep him by my side a bit longer.

Hello, my almost 10 yr old Golden Retreiver was recently diagnosed with proteinuria. I was given omega 3 and blood pressure medication along with 1/2 pill of baby aspirin daily. The vet also changed his food to k/d. How long do I have to wait to see a change on him. He is not very active and has poor appetite.

is ple more often caused by an autoimmune thing or more by cancers and the other cause I've read about. I have one vet saying one thing and another saying the opposite. They both stand by what they are saying and basically just short of the other is wrong

I need some advice please. So my dog Sway has what we thought was PLE caused by Lymphangiectasia. His albumin level 2 months ago was 1.7. He lost 5 lbs in less than a month, and had low vitamin B. So after a month on a strict low fat, high protein diet, vitamin supplements he had gained 4 lbs back, no more diarrhea, solid stool, and is in great spirits all in all. For the past week or so we have been checking his total protein in hope that if the TP was coming up then his Albumin level should and would also go up. His TP started at 4.8 and had risen to 5.5. His Globulin level has also raised. So everyone was feeling great about these numbers and that we were making some type of progress. Well those spirits crashed like the Titanic yesterday when the results came back that his Albumin level was still at 1.7! It hasn't decreased but sadly it has risen either. The consensus is that he is losing most of the protein through his urine. Which apparently is Protein losing NEPHROPATHY. So we did a urine test, that consisted of 3 separate samples combined into one to check his protien/creatine (not sure about that spelling) ratio. Those results will be back to tomorrow. Most likely cause of this is kidney disease, or impaired kidney of some type. Now here comes my heart wrenching dilemma....The vet wants him to start taking a drug called CellCept, generic name Mycophenolaye Mofetil. This drug is a immune suppressant that has some serious side effects that can and most likely will (due to my research) cause severe diarrhea, vomiting, and anorexia! It also has the risk to raise the chance of lymphoma! So I have this drug that is suppossed to help him but has a high chance of making him sicker and more importantly reverse the progress we have made. I know that if he develops diarrhea, and or vomiting he will lose even more protein through his intestines and additionally through his urine. They say that benefits can out weigh the risks but I'm just not seeing how that is possible. This medicine scares the ever living crap out of me, to a point that I am suffering from extreme anxiety from it. He is supposed to start taking it today but I'm struggling to give it to him morally. The nearest emergency vet is over a hour away and that doesn't sit well with me either if god forbid over the weekend he has some reaction to this drug and I am without immediate vet care. So I'm telling myself i will give it to him Monday, if nothing else to make me feel better for not giving it to him today. Does anyone have any knowledge, or personal experience with this drug?

I need some advice please. So my dog Sway has what we thought was PLE caused by Lymphangiectasia. His albumin level 2 months ago was 1.7. He lost 5 lbs in less than a month, and had low vitamin B. So after a month on a strict low fat, high protein diet, vitamin supplements he had gained 4 lbs back, no more diarrhea, solid stool, and is in great spirits all in all. For the past week or so we have been checking his total protein in hope that if the TP was coming up then his Albumin level should and would also go up. His TP started at 4.8 and had risen to 5.5. His Globulin level has also raised. So everyone was feeling great about these numbers and that we were making some type of progress. Well those spirits crashed like the Titanic yesterday when the results came back that his Albumin level was still at 1.7! It hasn't decreased but sadly it has risen either. The consensus is that he is losing most of the protein through his urine. Which apparently is Protein losing NEPHROPATHY. So we did a urine test, that consisted of 3 separate samples combined into one to check his protien/creatine (not sure about that spelling) ratio. Those results will be back to tomorrow. Most likely cause of this is kidney disease, or impaired kidney of some type. Now here comes my heart wrenching dilemma....The vet wants him to start taking a drug called CellCept, generic name Mycophenolaye Mofetil. This drug is a immune suppressant that has some serious side effects that can and most likely will (due to my research) cause severe diarrhea, vomiting, and anorexia! It also has the risk to raise the chance of lymphoma! So I have this drug that is suppossed to help him but has a high chance of making him sicker and more importantly reverse the progress we have made. I know that if he develops diarrhea, and or vomiting he will lose even more protein through his intestines and additionally through his urine. They say that benefits can out weigh the risks but I'm just not seeing how that is possible. This medicine scares the ever living crap out of me, to a point that I am suffering from extreme anxiety from it. He is supposed to start taking it today but I'm struggling to give it to him morally. The nearest emergency vet is over a hour away and that doesn't sit well with me either if god forbid over the weekend he has some reaction to this drug and I am without immediate vet care. So I'm telling myself i will give it to him Monday, if nothing else to make me feel better for not giving it to him today. Does anyone have any knowledge, or personal experience with this drug?