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Ibuprofen Poisoning in Dogs
Written By hannah hollinger
Published: 06/30/2016Updated: 03/29/2022
Veterinary reviewed by Michele K.
What is Ibuprofen Poisoning?
Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) used to treat pain, fever, and inflammation in humans. It's available in many generic forms, but the most common brand names include Advil, Midol, and Motrin. 
Most people have ibuprofen in their medicine cabinets, purses, drawers, or just somewhere in their house. It's a common medication many of us take without a second thought, which makes it one of the most common causes of poisoning in dogs. While it's suitable for human use, a very small amount of ibuprofen can be harmful to a dog. 
As well as reducing inflammation, ibuprofen also reduces the production of substances used to protect the lining of the stomach; this is what causes stomach ulcers in many toxicity cases. Other side effects can include other gastrointestinal distress, renal failure, and damage to the central nervous system.
If your pet ingests ibuprofen, seek veterinary attention straight away. If you see your pet consume the medication, you can induce vomiting to avoid the body beginning the absorption process. But if your pet ingests a significant amount or if you don’t realize it until some time has passed, contact your vet immediately.
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Ibuprofen Poisoning Average Cost
From 58 quotes ranging from $500 - $6,000
Average Cost
$2,100

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Symptoms of Ibuprofen Poisoning in Dogs
Some symptoms of ibuprofen poisoning in dogs, like vomiting and diarrhea, occur quickly, either immediately or within a few hours. Other symptoms, like stomach ulcers, may take longer to develop. Long-term and short-term symptoms include:
Types
Ibuprofen is the generic name of the drug. It's also known by brand names such as Advil, Motrin, and Midol. Ibuprofen is also used as an ingredient in some allergy medications and other products. However, the generic name of "ibuprofen" legally has to be on the medication label, so if you're unsure whether a product contains this drug, just check the label. Ibuprofen is available as a liquid or pill.
Causes of Ibuprofen Poisoning in Dogs
Ibuprofen is quickly absorbed after it is consumed and begins to inhibit the production of COX-1 enzymes. COX-1 enzymes produce the protective layer of the stomach, help maintain renal blood flow, and help platelets to clot when needed. Since ibuprofen works against and prevents the production of these substances, it can be very dangerous to dogs. 
Some well-intentioned pet parents give their dog ibuprofen for pain relief, believing it's safe. In other situations, a dog may help themselves to their human's medication, with the sweet coating on some ibuprofen tablets increasing the chance of ingestion.
Diagnosis of Ibuprofen Poisoning in Dogs
If there's even a slight chance your dog ingested ibuprofen, please contact your veterinarian immediately. Your vet will conduct a physical exam, looking for any of the side effects listed above. Blood work might also be recommended to get a better assessment of the damage. Key tests include:
  • Complete blood count (CBC)
  • Chemistry panel
  • Urinalysis
  • Renal panel
If you can, bring the medication packaging with you to the vet so they know exactly what your dog consumed.
Treatment of Ibuprofen Poisoning in Dogs
The outcome of ibuprofen poisoning treatment depends on the amount of ibuprofen your dog ingested and how quickly you react. If inducing vomiting doesn’t work, your veterinarian may give your pet activated charcoal at intervals throughout the day. This will prevent the GI tract from absorbing the medication and hopefully prevent the advancement of side effects.
Some severe cases of ibuprofen poisoning may require fluid therapy, flushing of the stomach, additional anti-vomiting or antacid medication, blood transfusions, or other supportive care.

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Recovery of Ibuprofen Poisoning in Dogs
The sooner you take your pet to the veterinarian, the higher their chances of a full recovery. The prognosis for dogs diagnosed and treated quickly is good. However, if you wait too long to take your pet to the veterinarian, or if they consumed more than their system can handle, it's possible treatment will fail. Always keep human medications and other toxins out of your pets' reach.
Ibuprofen poisoning can be expensive to treat. If you suspect your dog is at risk of ibuprofen poisoning, start searching for pet insurance today. Wag!’s pet insurance comparison tool lets you compare plans from leading companies like PetPlan and Embrace. Find the “pawfect” plan for your pet in just a few clicks!
Ibuprofen Poisoning Average Cost
From 58 quotes ranging from $500 - $6,000
Average Cost
$2,100
Top
Ibuprofen Poisoning Questions and Advice from Veterinary Professionals
Beagle
Two Years

4 found this helpful

4 found this helpful

My pet has the following symptoms:
I caught him chewing on an empty 200mg Advil liquigel. He weighs about 24 pounds (he’s taller than average, not fat)
March 4, 2021
Answered by Dr. Michele K. DVM
4 Recommendations
Thank you for your question. From your description, I'm not sure if your dog has a problem or not. There are many more details that I would need to know, like did they eat the capsule and is empty or was it empty and they ate it? When did this happen? How are they doing, is there any diarrhea or vomiting? The best thing to do may be to call your veterinarian or the nearest ER, and let them know what is going on, so that they can get the details needed to give you the right information. I hope that your dog is okay.
March 4, 2021
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Pug
4 months

6 found this helpful

6 found this helpful

My pet has the following symptoms:
None Yet
I’m not positive but I think my puppy may have eaten an ibuprofen pill but I’m not 100% sure 😩😩😩about 10 minutes ago
Sept. 27, 2020
Answered by Dr. Michele K. DVM
6 Recommendations
Thank you for your question. I am sorry for the delay, this platform is not set up for urgent emails. I hope that your pup is okay and did not eat the pill. For future reference, it would be best for a possible toxin emergency to call either a 24 hour clinic in your area, or a Pet Poison Control Hotline, and have both your dogs weight and the name and strength of mediation or other possible thing that your dog may have eaten. They will be able to help you determine quickly whether you need to take action or whether things will be okay.
Oct. 10, 2020
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Shihpoo
Thirteen Years

1 found this helpful

1 found this helpful

My pet has the following symptoms:
Vomiting
I’m not sure what my dog ate, she got into an old bag that I think had some ibuprofen spilled at the bottom. She has thrown up several times and won’t eat (this is the first time in her life she has refused food)
Sept. 27, 2020
Answered by Dr. Michele K. DVM
1 Recommendations
Thank you for your question. . It would be best to have your pet seen by a veterinarian, as they can examine them, see what might be going on, and help get treatment if it is appropriate.
Oct. 13, 2020
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Australian Shepherd
Five Months

7 found this helpful

7 found this helpful

My pet has the following symptoms:
Vomiting
I found my dog laying on his bed, next to a pile of vomit. He was chewing on a pill container that contained Advil Liquid gels. I have no idea if he swallowed any before throwing up or if he threw up from all his crazy running around (which happens to him on occasion)
Aug. 6, 2020
Answered by Dr. Michele K. DVM
7 Recommendations
Thank you for your question. That is quite a serious problem. It would be best to have him seen by your veterinarian right away, and if he were my dog and I weren't sure if he had eaten any or a lot of the medication, I would have him hospitalized on IV fluids and check kidney values for 48 hours. I hope that he is okay.
Aug. 6, 2020
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Dachshund
Four Months

6 found this helpful

6 found this helpful

My pet has the following symptoms:
None Right Now
My dog swallowed ibuprofen about 10 minutes ago he is 4 month dachshund and I am so worried he swallowed 1 pill but it was 200 mg please help!
Aug. 1, 2020
Answered by Dr. Michele K. DVM
6 Recommendations
Thank you for your question. That is high dosage of ibuprofen for a small dog. It would be best to have him seen right away, either by your veterinarian, or at an ER. They can determine if he needs IV fluid therapy, and can examine him and prescribe stomach protectants if needed. I hope that he is okay.
Aug. 1, 2020
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Labrador Retriever
Delilah
5 Years

0 found this helpful

0 found this helpful

My pet has the following symptoms:
None
My 4 year Labrador ate one 200mg ibruprofen she weighs (33kg) 72lbs, she seems fine but really worried, will she be okay? I don’t think I could get her to a vet tonight but I think she’s within the threshold she might be okay?
pitbull
Zeus
5 Months

0 found this helpful

0 found this helpful

My pet has the following symptoms:
Vomiting
My month old pitbull ate almost a half of a bottle of ibuprofen and he's been fine for several days now. Just vomiting a couple times about every 4 hours or so.
Newfoundland
Merrick
6 Years

0 found this helpful

0 found this helpful

My pet has the following symptoms:
None
Hello! My 135lb (61kg) male Newfoundland (6yo) ate somewhere between 600 to 1000mg of Advil last night. I don’t have the finances for an emergency vet visit so researched online and have monitored him since—no signs of any abnormalities so far (18hrs later). He’s been urinating, pooping, sleeping, drinking, and eating like normal. No vomiting. Stools are solid and no blood present. I will continue to monitor him closely, but I am wondering—given his weight and the mg he ingested, what is the risk of internal organ damage? I was told by his previous owner that he once ingested a box of rat poison with seemingly no effects, so he seems pretty hearty!
Mix
Brodi
7 Months

1 found this helpful

1 found this helpful

My pet has the following symptoms:
Vomiting
My puppy got a hold of a bottle of Ibuprofen sometime between 9:30PM and 2:30 AM. I woke up at 2:30 AM, gave him a scratch then he hopped to the other side of the room to throw up. When that happened, I turned the lights on to realize that he had gotten into the bottle cleaned up all the pills and called Animal Poison Control. Guessing that he could have taken up to 15-25 200mg tablets, the operator encouraged me to take him to a over night veterinary clinic. We were able to get him there by 4:00 AM and they almost immediately went to work on him (they gave him charcoal medication, did blood work on him, and started him on fluids). From there, we took him to my local Animal Hospital to get a steady 48 hours of fluid. When I first brought him in his kidney reading was 1.6, now (I am meant to pick him up from his 48 hour hold today) his reading is 2.1. They decided to keep him on fluids for a few hours longer. Could this be Ibuprofen poisoning or Kidney Damage? I am so so worried for him and don't know what to do. Could this damage be reversed? How can I help him? **He threw up twice at home (before heading to the clinic) and once in the car (once we arrived at the clinic) He has not thrown up since but has had diarrhea once while at the hospital but they did not seem too worried since he was on fluid.
jack russell mix
Jackie
4 Years

0 found this helpful

0 found this helpful

My pet has the following symptoms:
None Yet
My dog got ahold of an ibuprofen tablet somehow, but I believe it was only one and she didn’t actually eat it, just licked off the coating. Is the coating still dangerous? Should I take her to the vet? She is not showing any symptoms yet but it has only been 20-30 minutes since I found her with it. She weighs about 15 pounds.
Ibuprofen Poisoning Average Cost
From 58 quotes ranging from $500 - $6,000
Average Cost
$2,100

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