My dog ​​is diagnosed with chronic leukemia. the symptoms developed in a month so that even the veterinarian was convinced he was acute but the lab says he is chronic. he is currently on leukeran tablets and corticosteroids. he lost 8 kg and his dental meat was completely white. the blood picture is repaired since the therapy but the pounds are not climbing and the dental flesh is still completely white. The question is whether the kilograms should come back and the color of the dental flesh to repair if the therapy work

My vet recently prescribed both Palladia and hydroxyurea and the choice is up to me what to use. My dog has CML with a WBC too high to register on the machines... What is my best option? Is this blast crisis? I have read convincing literature on both drugs but remain divided on my best option.

Hi- my dog was recently diagnosed with CML Leukemia with myelopthesis however I am not sure if I am convinced. Based on the blood I have posted below- he responded well initially to another round of antibiotics with his WBC dropping from 100s into the 80s (which isn't reflected on the blood work chart for some reason) unfortunately it has remained in the 80's from there. Is it worth it to start chemo? When I ask the doctor I get very vague answers that it doesn't always work.. Should I be getting another opinion? I am still not totally convinced that this is cancer- his WBC seemed to sky rocket once he was on pred for awhile the problem is- when I take him off of pred his platelets drop. PREVIOUS DIAGNOSTICS 6-17-17 WBC 100,610 Segs 83,130 Hct 19.8% MCV 82 MCHC 36 Platelets 106,000 5-17-17 WBC 49,510 Segs 43,840 Hct 22% MCV 70 MCHC 38 Platelets 49,000 4-14-17 WBC 16,40 Segs 14,200 Hct 37% MCV 71 MCHC 35 Platelets 65,000 DIAGNOSTICS Path review: severe left shifted neutrophilia nad monocytosis, anemia, possible thrombocytopenia DIAGNOSIS Leukemoid reaction vs Myelogenous Leukemia DISCUSSION I strongly suspect CML Leukemia with myelopthesis. Submitted blood for path review. 6-26-17 emailed cytology, CBC report to owner 6-30-17 Wt 22.8#; Chest Rad: Normal; CBC: WBC 113,590 Segs 98,510, Hct 22.9%, Platelets 60,000; Prescribed Doxycycline 100ml bid, continue pred 7-14-17 Wt 25.4#; CBC: WBC 67,500 hct 28% Platelets 121,000; Continue meds, recheck 2 weeks 7-28-17 Wt 26.1#; WBC 76,170 Segs 69,600 Hct 30% Platelets 60,000; Pred 10mg daily Re: Beattie, Taco 8-18-17 Wt 28.6#; CBC: WBC 88,010 Neut 76,180 Hct 32.9% Platelets 17,000; Treatment of CML is best managed with chemotherapy to control the proliferation of the abnormal cell line and improve quality of life. Hydroxyurea is the most effective agent and is given at a dose of 20mg/kg bid until Neutrophilia counts fall to 15,000-20,000cells then the dose is reduced to 200mg twice per week

Hi. My 9 year old golden retriever Tulla was diagnosed with chronic lymphocytic leukemia march this year. We have started treating her with chlorambucil(leukeran) every other week combined with bloodwork to monitor her blood cells, and prednisone every other day. She had enlarged lymph nodes in her neck, under her chin and behind her heels when she was diagnosed, and no other symptoms. She was so unfortunate to get pyometra up in all this, so she had to remove her uterus. She seems happy and has gone up 1 kg, since her diagnosis, is eating well and likes to excercise in the woods, but I can see that she is not so energetic as before relating to long runs and high intensity. She is reacting to the chlorambucil and prednisone treatment well, and her lymph nodes went immediately down, where we can't fell them anymore, or we can feel a little bump, but she has one left on her right shoulder that is a little bit more hard to get rid of, but it is decreasing a little at a time. She is coughing a little bit and is sometimes short of breath and snores. I have 2 questions that I am wondering about. She scratches her stomach more than before, and the colour of her stomach is a little bit darker than before. This have occurred after her surgery to remover her uterus. The other question is about vitamins. I read in your article that the veterinarian may suggest giving vitamins, and I was wondering what vitamins that might be? Best regards, Maria and Tulla from Norway.

5 months ago, my dachshund developed lameness and lost energy and interest in surroundings (getting up to greet us, food, playing with his sister). Noticed all pads on all feet were peeling off, not the whole pad but just the top layer. All feet! Off to the vet and had high WBC and neutrophils so over the course of a few weeks had a couple of antibiotic injections and took several antibiotic tablets. Also had heavy breathing and started heart meds in case it was heart related. Had weight loss. Lung, heart, abdomen, liver etc all clear on xrays and ultrasounds. Stopped all anti-inflammatory and antibiotics and started on predisinone. Bloods have been monitored every few weeks and while still high, the WBC and Neuts are coming down. But after 2-3 months taking pred, his bloods are starting to rise again - could be cause he has started tappering his dosage or could be cause the pred is now no longer working and masking whatever is wrong. No confirmed diagnosis has been received and vets have the opinion of "we'll just keep doing what we're doing"... I need to know if there are any further tests that should be getting done, why are the bloods rising, whats wrong with him etc!

My min pin has leukemia. She has all the typical symptoms but- she also has chronic runny nose. A clear liquid with consistency of water. At night it runs literally like a faucet. She wakes up because she can’t control it , has to stand up to get control. This happens off and on all night. Can you tell me why this happens? Thanks